The effects of oxygen deprivation (hypoxia) at altitude are insidious as most individuals will not recognize that they are experiencing the condition. From
http://www.dr-amy.com/rich/oxygen/:
"For the normal individual, the affects of hypoxia are not detectable below pressure altitudes of 10,000 feet. Above 10,000 feet, the deleterious affects of hypoxia increase slowly at first, but then rapidly as altitude is increased above approximately 12,000 feet. Complex eye-hand coordination such as is required to maintain airspeed, heading, or vertical velocity decreases approximately 10% at 12,000 feet and 20-30% at 15,000 feet. At 12,000 feet, the dark-adapted eye begins to experience significant deterioration in vision. Unconsciousness may occur at altitudes as low as 16,000 feet in some individuals. The most dangerous aspect of hypoxia is that the individual experiencing hypoxia does not and cannot detect the decrement in function and loses the ability for critical judgement."
Given these conditions I would say you could use the 'wounded pilot' rules as they appear in the
WGF RAP for aircraft flying above 15,000 feet - 4 turns to clear a gun jam, no shooting after a steep manoeuvre. Of course this would not apply to aircraft fitted with oxygen cylinders, which were standard in high altitude two seaters such as the Rumpler C.IV and as the war progressed were often installed into single seat scouts as well.
Some pilots would also attempt to acclimatize their bodies by purposely flying at high altitude for prolonged periods, much the same as mountain climbers do when preparing for an assault on Everest for example. Medical research has identified however that such a process which requires weeks to complete will offset the impact of hypoxia on the body, it will not completely nullify the effects (
http://www.everestnews.com/stories20...ss01112005.htm)
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